Organelle crosstalk in disease
Metabolism and innate immunity through the lens of lipids and membranes.
At the IGBMC in Strasbourg, the Ricci Lab explores how membranes and organelles orchestrate inflammation and metabolic control. By examining inflammasome assembly in macrophages, neuroendocrine regulation in the hypothalamus, and insulin secretion in beta cells, we aim to uncover shared principles of membrane and organelle function in health and disease. Our mission is to translate these insights into novel strategies against chronic inflammatory and metabolic diseases.
IGBMC · Inserm · CNRS · University of Strasbourg
Macrophage
Membrane contact sites · endosome stress · inflammasome activation · inflammatory diseases
Hypothalamic neuron
Neuroendocrine control · membrane remodeling · food intake regulation · obesity
Pancreatic β cell
Membrane contact sites · insulin granule turnover · autophagy · type 2 diabetes
Latest publications
News
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HDR of Karl Vivot
After receiving a CRCN position at Inserm, Karl will defend his habilitation in autumn of this year.
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Chaire d'excellence France 2030
Romeo Ricci has been awarded a Chair of Excellence for his ENDOFLAMMASOME project.
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Minisymposium at IGBMC
On the day of Karl's HDR defense, we organize a minisymposium with committee members at the IGBMC.
